Glyphosate
Overview
Glyphosate cancer risk is scientifically and politically contested. IARC classified glyphosate as probably carcinogenic to humans based on hazard evaluation, including limited human evidence and animal/mechanistic data. EPA reviews have weighed the evidence differently in regulatory risk assessment. The strongest concern is occupational or high-exposure contexts such as agricultural use, herbicide application, and repeated contact with glyphosate-based formulations. For the database, the fair description is that glyphosate may contribute to cancer risk under certain exposure conditions, but agencies differ in how they interpret the total evidence.