Randomized phase 2 NCT03678883 report of elraglusib plus gemcitabine/nab-paclitaxel in first-line metastatic pancreatic ductal adenocarcinoma.
PC-SPES / PC-HOPE / PC-CARE / PC-PLUS
Chinese-herb prostate formula family, with PC-SPES withdrawn after contamination/adulteration concerns. PC-SPES was a patented eight-herb mixture promoted for prostate health/prostate cancer. NCI PDQ notes some batches contained prescription medicines and the original product was withdrawn; later products claiming to substitute for it are not the same patented formula. PROS Historical prostate-cancer herbal formula data can be reviewed cautiously.
Randomized controlled trial of 58 cancer patients; 4-week EFT plus routine care improved anticipatory grief, anxiety, and sleep quality versus routine care alone.
Preclinical study reporting that fasting-mimicking diet restored sensitivity to CDK4/6 inhibition and potentiated anti-tumor activity in breast cancer models through suppression of IGF1/RAS-associated mTORC1 signaling. Useful for tracking FMD plus targeted-therapy hypotheses.
NCI professional summary: patented eight-herb prostate formula; product withdrawn after contamination/adulteration concerns; substitutes are not original PC-SPES.