This site is still under development. Information, features, and some organizational
aspects of the data still need further work and will change as we continue building.

Pap/HPV Cotest

Hover over a term you want explained. If you need more details, then click on the term and a new tab will open with a full details page.

What the Pap/HPV Cotest Means

The Pap/HPV cotest is a cervical cancer screening method that combines two important tests done at the same time. The first is the HPV test, which looks for certain types of human papillomavirus (HPV) that are considered high-risk because they can lead to cervical cancer. The second is the Pap test (also called a Pap smear), which examines cervical cells for abnormal changes that might develop into cancer if left untreated. Often, the same sample of cervical cells is used for both tests, making the process efficient and convenient.

Why This Test Matters in Cancer Care

Cervical cancer usually develops slowly and may not cause symptoms in its early stages. Screening with the Pap/HPV cotest helps find high-risk HPV infections and abnormal cervical cells before cancer develops or when it is easier to treat. Because the cotest checks for both the virus and cell changes, it is more likely to detect problems early compared to a Pap test alone. Early detection through screening can prevent cervical cancer or catch it at a stage when treatment is more effective.

What to Expect During the Test

The Pap/HPV cotest is usually done during a pelvic exam, which takes only a few minutes. Your healthcare provider will collect cells from your cervix using a small swab or brush. You might feel some mild discomfort, but the test is generally quick. After the test, your provider will explain when to expect results and what the next steps might be if any abnormalities are found.

Understanding Test Results and Follow-Up

A Pap/HPV cotest is a screening tool, not a diagnosis. A positive HPV test or abnormal Pap result does not mean you have cervical cancer. It means further testing or closer follow-up may be needed to understand the cause. A normal result does not guarantee you will never develop cervical cancer, so regular screening as recommended is important. If your results are abnormal, your healthcare provider may suggest additional tests, such as a biopsy, to get more information.

Who Should Get the Pap/HPV Cotest and How Often

Screening guidelines recommend that people aged 30 to 65 get cervical cancer screening with either an HPV test alone every 5 years, a Pap/HPV cotest every 5 years, or a Pap test every 3 years. For those younger than 30, Pap testing every 3 years is usually recommended. Your healthcare provider will consider your age, health history, and risk factors to recommend the best screening plan for you.

Common Questions to Ask Your Healthcare Provider

If you have questions about the Pap/HPV cotest, you might ask why this test is recommended for you, how often you should have it, what the results mean, and what follow-up steps might be needed. Understanding your screening schedule and results can help you feel more confident about your health care.

Important Notes About This Information

This information is educational and does not replace personalized advice from your healthcare provider. Your provider will consider your individual health needs to recommend the best screening plan. Staying up to date with cervical cancer screening, including the Pap/HPV cotest when appropriate, is an important way to protect your health.

Next Steps

If you have a cervix, talk with your healthcare provider about when to start cervical cancer screening, how often to be tested, and what to expect during the process. Regular screening helps find problems early, when treatment is most effective.

Sources

Public source information used for this glossary entry includes: